What is Atherosclerosis?

It is the major cause of heart attack, some strokes, aneurysms, and peripheral artery disease.

Our arteries are much more than simple tubes. They build a well organized tubing system that supply the organs and tissues of the body with the blood they need to extract sufficient amounts of nutrients and oxygen. 

Arteries also regulate blood flow and pressure through a complicated system of hormones and flow-sensitive receptors, work as a first alarm system for local infections and injury as well as regulating the subsequent repair process.

In the best of all worlds the artery would manage these challenges quite well keeping its wall slim and elastic. However, with the
conditions facing the artery wall in most of us today with a continuous exposure to high levels of potentially toxic lipids and other factors fulfilling these tasks may come with a high price, the development of inflammation, scaring and disruption of the inner layer of the artery. This disease is called atherosclerosis and makes the artery wall thickened, stiff and fragile.

 

Atherosclerosis Redefined

Recent discoveries have inspired new hope for the prevention and treatment of atherosclerosis. In turn, these discoveries have created a major paradigm shift in the medical community's understanding of the disease, and it is now known that atherosclerosis is beyond a metabolic disorder.

It is indeed an inflammatory disease, and the body's immune system plays a central role in the initiation, as well as complication of, atherosclerotic plaques.

In the wake of this paradigm shift, new therapeutic avenues to treat these plaques are being opened.


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Among them, immune modulation and vaccination strategies The AEHA Vaccine Initiative - A Preliminary Proposal (PDF)are most intriguing. The Association for Eradication of Heart Attack believes that such ground-breaking strategies can become the basis of curing the world's growing epidemic of heart disease.

 

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Quiz & Poll
  Patient's Question
Which condition is more dangerous? (better predicts a near future heart attack)
    High blood cholesterol
    High coronary calcium
  Doctor's Question
Would you treat individuals with normal cholesterol but high coronary calcium or carotid IMT?
    No
    Yes